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Chao Chen Selected Research

Glioblastoma (Glioblastoma Multiforme)

8/2023FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1.
8/2023Identification of Necroptosis-related Molecular Subtypes and Construction of Necroptosis-related Gene Signature for Glioblastoma Multiforme.
10/2022ATF4-dependent fructolysis fuels growth of glioblastoma multiforme.
10/2021DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis.
1/2019Neddylation inhibition upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma.
1/2019LncRNA SAMMSON overexpression distinguished glioblastoma patients from patients with diffuse neurosarcoidosis.
7/2017Revealing radiotherapy- and chemoradiation-induced pathway dynamics in glioblastoma by analyzing multiple differential networks.
2/2016Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.
1/2015Polymorphisms in IL-4/IL-13 pathway genes and glioma risk: an updated meta-analysis.
5/2013Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population.
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Chao Chen Research Topics

Disease

300Neoplasms (Cancer)
07/2024 - 07/2006
69Infections
02/2024 - 02/2007
53Inflammation (Inflammations)
03/2024 - 08/2009
49Neoplasm Metastasis (Metastasis)
04/2024 - 04/2008
30Carcinogenesis
02/2024 - 09/2011
30Hypoxia (Hypoxemia)
09/2023 - 08/2009
27Breast Neoplasms (Breast Cancer)
02/2024 - 09/2011
25Fibrosis (Cirrhosis)
02/2024 - 05/2009
25Stomach Neoplasms (Stomach Cancer)
11/2023 - 07/2008
24Lung Neoplasms (Lung Cancer)
04/2024 - 09/2013
24Glioma (Gliomas)
08/2023 - 09/2011
20Hepatocellular Carcinoma (Hepatoma)
01/2024 - 01/2012
17Pain (Aches)
04/2024 - 01/2010
17Colorectal Neoplasms (Colorectal Cancer)
03/2024 - 06/2012
16Schizophrenia (Dementia Praecox)
05/2024 - 08/2011
16Parkinson Disease (Parkinson's Disease)
01/2024 - 11/2012
14Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2024 - 01/2014
14Prostatic Neoplasms (Prostate Cancer)
03/2024 - 05/2012
14Body Weight (Weight, Body)
12/2023 - 12/2012
14Type 2 Diabetes Mellitus (MODY)
09/2023 - 01/2015
13Wounds and Injuries (Trauma)
04/2024 - 10/2017
12Insulin Resistance
04/2024 - 08/2017
12Bronchopulmonary Dysplasia
01/2024 - 11/2009
12Hemorrhage
12/2023 - 05/2012
12Glioblastoma (Glioblastoma Multiforme)
08/2023 - 01/2013
12Sepsis (Septicemia)
03/2023 - 02/2007
12Birth Weight (Birth Weights)
02/2023 - 02/2010
10Bacterial Infections (Bacterial Infection)
01/2024 - 12/2010
10Heart Failure
01/2024 - 05/2012
10COVID-19
01/2022 - 01/2020
9Psoriasis (Pustulosis Palmaris et Plantaris)
05/2024 - 01/2020
9Brain Neoplasms (Brain Tumor)
02/2024 - 05/2013
9Myocardial Infarction
12/2023 - 04/2010
9Acute Lung Injury
01/2023 - 12/2013
9Liver Neoplasms (Liver Cancer)
01/2022 - 10/2012
9Papillary Thyroid Cancer
01/2022 - 01/2015
9Retinopathy of Prematurity (Retrolental Fibroplasia)
10/2021 - 04/2006
8Pancreatic Neoplasms (Pancreatic Cancer)
05/2024 - 01/2013
8Disease Progression
04/2024 - 01/2020
8Alzheimer Disease (Alzheimer's Disease)
03/2024 - 10/2010
8Spinal Cord Injuries (Spinal Cord Injury)
11/2023 - 02/2014
8Acquired Immunodeficiency Syndrome (AIDS)
12/2022 - 04/2016
7Mitochondrial Diseases (Mitochondrial Disease)
05/2024 - 10/2012
7Hyperthermia
04/2024 - 02/2015
7Leukemia
03/2024 - 01/2014
7Osteoporosis
03/2024 - 05/2013
7Urinary Bladder Neoplasms (Bladder Cancer)
02/2024 - 03/2011

Drug/Important Bio-Agent (IBA)

91Proteins (Proteins, Gene)FDA Link
05/2024 - 02/2007
73Biomarkers (Surrogate Marker)IBA
05/2024 - 08/2011
55MicroRNAs (MicroRNA)IBA
12/2023 - 05/2011
26Messenger RNA (mRNA)IBA
11/2023 - 02/2007
25DNA (Deoxyribonucleic Acid)IBA
12/2023 - 06/2008
24CytokinesIBA
02/2024 - 06/2005
23RNA (Ribonucleic Acid)IBA
12/2023 - 05/2012
23EnzymesIBA
07/2023 - 01/2008
21Long Noncoding RNAIBA
01/2024 - 05/2012
21Oxygen (Dioxygen)IBA
10/2023 - 04/2006
18Glucose (Dextrose)FDA LinkGeneric
09/2023 - 01/2013
16Therapeutic UsesIBA
09/2023 - 02/2012
14Immune Checkpoint InhibitorsIBA
04/2024 - 01/2019
14Peptides (Polypeptides)IBA
11/2023 - 03/2012
14Circular RNAIBA
08/2023 - 01/2017
13Reactive Oxygen Species (Oxygen Radicals)IBA
01/2023 - 08/2012
12LipidsIBA
09/2023 - 10/2009
12Small Interfering RNA (siRNA)IBA
01/2022 - 04/2008
11Transcription Factors (Transcription Factor)IBA
04/2024 - 05/2013
11Anti-Bacterial Agents (Antibiotics)IBA
01/2024 - 01/2014
11Doxorubicin (Adriamycin)FDA LinkGeneric
06/2022 - 07/2010
10LipopolysaccharidesIBA
03/2023 - 12/2013
10Retinaldehyde (Retinal)IBA
01/2023 - 01/2007
10AntibodiesIBA
08/2022 - 01/2008
10Hemoglobins (Hemoglobin)IBA
01/2022 - 01/2013
9Cisplatin (Platino)FDA LinkGeneric
05/2024 - 01/2017
9BilirubinIBA
04/2024 - 07/2007
9Insulin (Novolin)FDA Link
04/2024 - 11/2015
9CreatinineIBA
04/2023 - 12/2012
9Photosensitizing Agents (Photosensitizers)IBA
01/2023 - 09/2017
9AcidsIBA
01/2023 - 06/2011
9CollagenIBA
01/2022 - 08/2009
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2021 - 08/2009
8FlavonoidsIBA
07/2024 - 10/2012
8Amino AcidsFDA Link
03/2024 - 12/2011
8Hormones (Hormone)IBA
02/2024 - 09/2011
8ProdrugsIBA
09/2023 - 12/2013
8Analgesics (Analgesic Drugs)IBA
01/2023 - 01/2014
81-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2023 - 09/2017
8Leucine (L-Leucine)FDA Link
08/2022 - 05/2013
8Formaldehyde (Formol)FDA Link
07/2020 - 10/2007
8arseniteIBA
11/2019 - 01/2017

Therapy/Procedure

157Therapeutics
05/2024 - 05/2008
31Drug Therapy (Chemotherapy)
02/2024 - 06/2008
26Immunotherapy
04/2024 - 12/2013
13Radiotherapy
02/2024 - 07/2010
12Lasers (Laser)
02/2024 - 12/2010
11Chinese Traditional Medicine (Traditional Chinese Medicine)
08/2023 - 05/2009
11Photochemotherapy (Photodynamic Therapy)
01/2023 - 01/2017
10Artificial Respiration (Mechanical Ventilation)
10/2023 - 06/2005
9Photothermal Therapy
01/2023 - 01/2017
8Length of Stay
01/2023 - 01/2013
7Radiofrequency Ablation
04/2024 - 01/2019